SHZ Members and Research Groups

SHZ Members:

Prof. Peter Achermann, PhD

Prof. Christian Baumann, MD

Prof. Konrad Bloch, MD

Prof. Steven Brown, PhD

Maren Cordi, PhD (associate)

Dario Dornbierer, PhD

Sebastian Holst, PhD (associate)

Prof. Reto Huber, PhD

Prof. Oskar Jenni, MD

Prof. Walter Karlen, PhD (associate)

Prof. Birgit Kleim, PhD

Prof. Malcolm Kohler, MD

Prof. Salomé Kurth, PhD

Prof. Hans-Peter Landolt, PhD

Prof. Bigna Lenggenhager, PhD

Caroline Lustenberger, PhD (associate)

Angelina Maric, PhD

Prof. Alexander Möller, MD

Marta Morawska, PhD

Daniela Noain, PhD

Ruth O'Gormann Tuura, PD PhD

Prof. Robert Riener, PhD

Sarah Schiebler, MD

Simon Schreiner, MD

Esther Irene Schwarz, MD

Prof. Erich Seifritz, MD

Benjamin Stucky, PhD

Laura Tüshaus, PhD (associate)

Prof. Philipp Valko, MD

Amandine Valomon, PhD (associate)

Helene Werner, PhD

Esther Werth, PhD

Elisabeth Wilhelm, PhD (associate)

 

Prof. Peter Achermann, PhD

member
 

KEY Institute for Brain-Mind Research (Link)

peter.achermann@uzh.ch

Research fields: Basic human sleep research

KFSP Sleep & Health (2012-2018): link

Publications: Pubmed

Prof. Christian Baumann, MD

member

 

Department of Neurology, University Hospital Zurich

christian.baumann@usz.ch

Research fields: Basic & clinical sleep research, new technologies

Research Focus: Neurology, Neurodegenerative diseases, Parkinson, Sleep disorders

KFSP Sleep & Health (2012-2018): link

HMZ Flagship SleepLoop: link

Collaborative projects with: Reto Huber, Walter Karlen, Erich Seifritz, Hans-Peter Landolt

Publications: Pubmed

 

SHZ Junior Members:

Sedef Erdogan, PhD candidate (sedef.erdogan@usz.ch)

Carlos Gonçalves Moreira, PhD candidate (carlos.goncalvesmoreira@usz.ch)

Niklas Schneider, PhD candidate (niklas.schneider@usz.ch)

 

Prof. Konrad Bloch, MD

member

 

Department of Pulmonology, University Hospital Zurich

konrad.bloch@usz.ch

Website: Department of Pulmonology

Research fields: Clinical sleep research, new technologies

Research Focus: Sleep related breathing disorders (clinical manifestation, diagnosis and treatmen), interactions between hypoxia and sleep

Questions driving my research: What are the physiological mechanisms of sleep related breathing disorders? How can they be diagnosed? How can they be treated?
What are the effects of exposure to hypobaric hypoxia at altitude on breathing and sleep? How can adverse effects of hypoxia due to environmental exposure or lung disease be prevented or treated?

Methodological expertise: Broad physiological and clinical monitoring of control of breathing, ventilation and sleep Randomized clinical trials in the hospital and field setting

Publications: Pubmed

Synergies with other sleep research groups: Silvia Ulrich, Malcolm Kohler, Reto Huber

Prof. Steven Brown, PhD

member

 

Institute of Pharmacology and Toxicology, UZHInstitute of Pharmacology and Toxicology, UZH

steven.brown@pharma.uzh.ch

Website: The Brown Lab

Research fields: Preclinical sleep research, Chronobiology

Research Focus: Molecular biomarkers and mechanisms for sleep and circadian dysfunction, biochemical and cell biological studies to explore novel mechanims in clock function

Methodological expertise: Molecular, biochemical, and cellular methods in mouse models and human cells; neural circuit-based investigations of sleep and circadian clocks in mouse models

KFSP Sleep & Health (2012-2018): link

Publications: Pubmed

Maren Cordi, PhD

member

 

University of Fribourg, Department of Psychology

Postdoctoral fellow

maren.cordi@unifr.ch

Team Cognitive Biopsychology and Methods (Prof. Björn Rasch)

Publications:Pubmed

Dario Dornbierer, PhD


Dornbierer

 

 

 

University Hospital of Psychiatry 

UZH Entrepreneur Fellow: Link to the project "Toward a safe, effective and rapid-acting treatment of mood disorders"

dornbierer@pharma.uzh.ch

Research fields: Basic human sleep research, clinical sleep research, new technologies

Research Focus: Psychedelic research, sleep pharmacology, pharmaceutical technology

Questions driving my research: Neuropharmacological mechansims of altered states of consciousness, 

neurochemistry of sleep, psychiatric drug repurposing

Methodological expertise: Sleep EEG, event-related potentials, MRS, blood biomarkers of neuropsychiatric disorders, 

pharmaceutical technologies

Publications: Pubmed

Synergies with other sleep research groups: Hans-Peter Landolt, Thomas Krämer, Boris Quednow, Milan Scheidegger, Erich Seifritz

Sebastian Holst, PhD


member

 

 

University of Copenhagen

Rigshospitalet, Neurobiology Research Unit

Junior Group Leader

sebastian.holst@nru.dk

Research fields: Basic sleep research

Research Focus: Specific interest in how sleep and sleep-loss affect the human brain and cognition, using pharmacology and ultra-fast brain imaging to investigate changes in brain pulsations between sleep, sleep deprivation and rested wakefulness.

Collaborative projects with:Hans-Peter Landolt

Publications: Pubmed

Prof. Reto Huber, PhD

member

 

University Children's Hospital Zurich

reto.huber@kispi.uzh.ch

Website: Link

Research fields: Basic human sleep research, new technologies

Research Focus: Sleep and brain maturation, Learning related plasticity and sleep regulation, Neurodevelopmental disorders, Neuromodulation during sleep, Local sleep, Multimodal imaging during sleep

Questions driving my research: What is sleep recovery? Does sleep play an active part in brain maturation? What is the potential of neuromodulation techniques during sleep as a therapeutic intervention? What is the relationship between different imaging modalities and sleep oscillations?

Methodological expertise: High-density EEG, Closed-loop acoustic stimulation, Multimodal neurimaging (MRI, MR spectroscopy, EEG)

KFSP Sleep & Health (2012-2018): link

HMZ Flagship SleepLoop: link

Publications: Pubmed

Synergies with other sleep research groups: Hans-Peter Landolt, Steven Brown, Christian Baumann Walter Karlen, Daniel Brandeis (UZH), Oskar Jenni, Bernhard Schmitt (University Children's Hospital Zurich)

 

SHZ Junior Members:

Joëlle Albrecht, PhD candidate (ioelle.albrecht@kispi.uzh.ch)

Elena Krugliakova, PhD candidate (elena.krugliakova@kispi.uzh.ch)

Jelena Skorucak, PhD (jelena.skorucak@pharma.uzh.ch)

Georgia Sousouri, PhD candidate (georgia.sousouri@kispi.uzh.ch)

Prof. Oskar Jenni, MD

member

 

University Children's Hospital Zurich

oskar.jenni@kispi.uzh.ch

Publications: Pubmed

Prof. Walter Karlen, PhD

member

 

ETH Zurich

Department of Health Sciences and Technology

Mobile Health Systems Lab

walter.karlen@hest.ethz.ch

Website: Link

Research fields: New technologies

Research Focus: Biomedical signal processing, mobile health (mHealth), adaptive algorithms and systems, embedded and wearable devices, mobile computing, biomedical sensors and systems, global health, appropriate devices, decision support, artificial intelligence, machine learning, pulse oximeter, capnography, pneumonia, dehydration, anesthesia, sleep, attention and fatigue. 

HMZ Flagship SleepLoop: link

Publications: Pubmed

Synergies with other sleep research groups: Christian Baumann, Reto Huber

Twitter: @mhsl_ethz

Prof. Birgit Kleim, PhD

member

 

Department of Psychiatry Psychotherapy and Psychosomatics (website)

birgit.kleim@puk.zh.ch

KFSP Sleep & Health (2012-2018): link

Publications: Pubmed

Prof. Malcolm Kohler, MD

member

 

Department of Pulmonology, University Hospital Zurich

malcolm.kohler@usz.ch

Website: Department of Pulmonology

Research fields: Clinical sleep research, new technologies

KFSP Sleep & Health (2012-2018): link

HMZ Flagship Exhalomics: Link

Publications: Pubmed

 

Prof. Salomé Kurth, PhD

member

 

Department of Pulmonology, University Hospital Zurich

Department of Psychology, University of Fribourg

salome.kurth@usz.ch

Websites: Baby Sleep Lab; Team Development of Sleep Regulation

Research fields: Basic human sleep research

Research Focus: Development of sleep regulation in childhood

Questions driving my research: Which parameters of infant sleep behavior represent a health risk for neurodevelopment? Are early sleep patterns a trait and thus persist throughout later life? Are there associations between sleep and the gut bacteria?

Methodological expertise: High-density EEG during sleep

KFSP Sleep & Health (2016-2018): link

Publications: Pubmed

Synergies with other sleep research groups: Malcolm Kohler, Reto Huber, Oskar Jenni, Steven Brown, Walter Karlen

Prof. Hans-Peter Landolt, PhD

member

 

Institute of Pharmacology and Toxicology, UZH

landolt@pharma.uzh.ch

Website: Human sleep Psychopharmacology Laboratory

Research fields: Basic human sleep research, clinical sleep research

Research Focus: Physiological processes and neurochemical mechanisms regulating wakefulness and sleep in health and disease.

Questions driving my research: What are the molecular mechanisms underlying the transition from wakefulness to sleep and from sleep to wakefulness? Who is vulnerable to sleep deprivation? How does sleep promote health? Can sleep be enhanced to benefit health?

Methodological expertise: Multidisciplinary, integrative approach combining pharmacogenetics, neurophysiology (polysomnography and [high-density] EEG), molecular brain imaging (PET, MRS) and neurocognitive testing

KFSP Sleep & Health (2012-2018): link

Publications: Pubmed

Synergies with other sleep research groups (Zurich): Christian Baumann, Erich Seifritz, Simon M. Ametamey (ETH Zürich), Reto Huber

 

SHZ Junior Members:

Diego Baur, PhD candidate (dmbaur@pharma.uzh.ch)

Ian Clark, PhD candidate (ian.clark@uzh.ch)

Dario Dornbierer, PhD (dornbierer@pharma.uzh.ch)

 

Prof. Bigna Lenggenhager, PhD

member

 

Department of Psychology, UZH

bigna.lenggenhager@psychologie.uzh.ch

Research fields: Basic human sleep research

Research Focus: Body perception and self-consciousness. Sleep/dreams as an altered state of self-consciousness.

Questions driving my research: How do we experience the body (and the feeling of ownership, agency) in dreams? How is body awareness and interoception (e.g. HEP) altered during different sleep stages? What do we learn from dreams and lucid dreams about body self consciousness? How does vestibular stimulation and or cortical stimulation alters dream contents?

Methodological expertise: EEG, questionnaires, tDCS, galvanic vestibular stimulation

Publications: Pubmed

Synergies with other sleep research groups: Robert Riener

Caroline Lustenberger, PhD

member

 

ETH Zurich

Department of Health Sciences and Technology

Neural Control of Movement Lab (Pof. N. Wenderoth)

Research fields: Basic human sleep research, new technologies

Research Focus: link

Methodological expertise: 

HMZ Flagship SleepLoop: link

Publications: Pubmed

Synergies with other sleep research groups: Christian Baumann, Reto Huber, Walter Karlen, Nicole Wenderoth

Angelina Maric, PhD

member

 

Department of Neurology, University Hospital Zurich

Postdoctoral fellow (Group Baumann)

Angelina.Maric@usz.ch

Research fields: Basic human sleep research, clinical sleep research, new technologies

Research Focus: Psycho-physiological sleep research in health and disease, with a special emphasis on the effects chronic sleep restriction.

Questions driving my research: How do sleep physiological processes influence brain functioning and corresponding behavior during subsequent wakefulness? What are the consequences of chronically insufficient sleep and the underlying mechanisms thereof? How do sleep physiological processes contribute to symptoms and progression of a neurological disease like Parkinson?

Methodological expertise: Performance of highly controlled, experimental sleep studies (e.g. sleep restriction protocols), including state-of-the-art neuroscientific methods like high-density sleep electroencephalography (hd-EEG) and comprehensive behavioral testing like elaborate decision-making paradigms.

Publications: Pubmed

Synergies with other sleep research groups: Reto Huber, Walter Karlen, Ernst Fehr (Department of Economics, UZH), Helga Fehr-Duda, (Institute of Banking and Finance, UZH), Ruth O’Gorman Tuura (Center for MR-Research, University Children's Hospital Zurich), Caroline Lustenberger, Salome Kurth

Prof. Alexander Möller, MD

member

 

University Children's Hospital Zurich

alexander.moeller@kispi.uzh.ch

Research fields: Clinical sleep research

Research Focus: Sleep disordered breathing in children and effects on development

Methodological expertise: clinical expertise

Synergies with other sleep research groups: Reto Huber, Oskar Jenni, Malcolm Kohler

Marta Morawska, PhD

member

 

Department of Neurology, University Hospital Zurich

Postdoctoral fellow (Group Baumann)

marta.morawska@usz.ch

Research fields: Basic preclinical sleep research

Research Focus: I am interested in the interplay between sleep and neurological disease and how improving sleep quality can alleviate symptoms and pathological protein burden in CNS disorders.

Questions driving my research: The fundamental question driving my research is the regenerative/protective function of sleep in the context of CNS disorders.

Methodological expertise: In vivo electrophysiology, behavioral pharmacology, histology and microscopy

Publications: link

Daniela Noain, PhD

member

 

Department of Neurology, University Hospital Zurich

Senior scientist (Group Baumann)

daniela.noain@usz.ch

Research fields: Basic preclinical sleep research

Research Focus: The focus of our research is exploring the role of slow-wave sleep in the levels of brain proteins that lead to neurodegeneration. Aiming at implementing translational and highly specific slow-wave sleep modulation strategies in transgenic rodent models of disease, we develop innovative techniques, such as closed-loop acoustic stimulation of slow oscillations. Our ultimate goal is providing tools for and proof that modulations of slow-wave sleep regulate protein clearance in the sleeping brain and, therefore, could be translated into novel non-invasive human therapies against Alzheimer and Parkinson Disease.

Questions driving my research: What restorative and/or neuroprotective processes unfold in the sleeping brain? s slow-wave sleep a key player to their regulation and execution? And, therefore: Could slow-wave sleep modulation be used to influence the course of neuropathological processes?

Methodological expertise: In vivo electrophysiology, Pharmacological modulation of slow waves, Acoustic modulation of slow waves, Behavioral testing, Histopathology
Stereology

Publications: Pubmed

Synergies with other sleep research groups: Reto Huber

Ruth O'Gorman Tuura, PD PhD

tuura

 

Department of Neurology, University Hospital Zurich

ruth.tuura@kispi.uzh.ch

Research fields: Basic and clinical sleep research, new technologies

Research Focus: As a physicist with a background in medical imaging (particularly MRI), my primary scientific interests are focused on advanced methods for evaluating brain physiology, including arterial spin labelling perfusion MRI, MR spectroscopy, diffusion tensor MRI, functional MRI, and quantitative MR Relaxometry. In addition to performing methodological studies with an aim to improve or cross-validate these methods, I have also performed a number of multimodal studies utilising multiple, complementary imaging methods to give a more complete and detailed picture of tissue morphology and function. This approach has yielded novel insight into the brain changes associated with sleep, as well as insight into brain development in children, both in healthy populations and in those at risk for neurodevelopmental impairment.

Questions driving my research: My research is inspired by a number of questions. On the methodological side, I am interested to push forward the imaging methods (and image analysis methods) available both to the clinics and to researchers interested in measuring brain physiology with MRI. In addition, I am interested in the development of brain structure and function in neonates, children, and adolescents, and in the assessment of neuroimaging biomarkers for outcome in children at risk for developmental impairment. Recently, I have also become fascinated with the potential role of sleep in clearing the brain, and how we might be able to measure and characterise this process in vivo with MRI.

Methodological expertise: MRI methods: arterial spin labelling perfusion MRI, MR spectroscopy, diffusion tensor MRI, functional MRI, quantitative MR Relaxometry, simultaneous EEG-fMRI

Publications: Pubmed

Synergies with other sleep research groups:  Christian Baumann, Reto Huber, Walter Karlen, Hans-Peter Landolt

 

Prof. Robert Riener, PhD

member

 

Faculty of Medicine (UZH), ETH Zurich

robert.riener@hest.ethz.ch

Research fields: Basic human sleep research, new technologies

Research Focus: Development of an autonomous robotic platform to improve sleep quality using vestibular stimulation. Controlled positional therapy to reduce snoring.

Questions driving my research: Improvement of health and well-being related to sleep.

Methodological expertise: Man-machine interaction. Rehabilitation Engineering

Biomechatronics & Biomedical Engineering. Virtual reality. Transfer of Technologies into Neurorehabilitation

Publications: Pubmed

Synergies with other sleep research groups: Hans-Peter Landolt, Reto Huber, Malcolm Kohler

 

SHZ Junior member:

Rachel van Sluijs, PhD candidate (rachel.vansluijs@hest.ethz.ch)

 

Sarah Schiebler, MD

member

 

University Hospital Zurich, Psychiatry

sarah.schiebler@usz.ch

Research fields: Clinical sleep research

Research Focus: Effects of different treatments (CBT-I, hypnotherapy, hypnotic drugs) of sleep disorders and sleep disturbances in mental and psychosomatic disorders

Questions driving my research: Which methods can effectively improve the diagnostic procedures and the treatment of sleep disturbances in psychiatric and psychosomatic disorders?

Methodological expertise: Completed training as a specialist and diploma in psychiatry and psychotherapy; Training in psychosomatic medicine and Consultation-Liaison-Psychiatry; Diploma of Cognitive Behavioral Therapy; Diploma of Advanced Studies in Psychotraumatology; Master in Hypnotherapy

Synergies with other sleep research groups: Philipp Valko

Simon Schreiner, MD

member

 

Department of Neurology, University Hospital Zurich

Postdoctoral fellow (Group Baumann)

simon.schreiner@usz.ch

Research fields: Clinical sleep research, new technologies

Research Focus: Neurodegenerative disorders, particularly Alzheimer disease and Parkinson syndromes. Role of sleep and sleep-modulation in neurodegenerative diseases

Methodological expertise: quantitative sleep EEG, Advanced neuroimaging with PET and MRI, including ultra-high field strength MRI at 7 Tesla

Publications: Pubmed

Twitter: @SJ_Schreiner

Synergies with other sleep research groups: Walter Karlen, Reto Huber, Philipp Valko

Esther Irene Schwartz, MD

member

 

Department of Pulmonology, University Hospital Zurich

Senior scientist (Group Kohler)

EstherIrene.Schwarz@usz.ch

Website: Department of Pulmonology

Research fields: Clinical sleep research

Research Focus: Pathophysiological consequences of obstructive sleep apnoea and chronic pulmonary disease, cardiovascular and metabolic effects of continuous positive airway pressure therapy and emerging treatment approaches for sleep- disordered breathing. Long-term outcome of chronic respiatory failure trated by non invasive ventilation, haemodynamic effect of positive pressure ventilation. Neural respiratory drive/electromyography in different respiratory diseases.

KFSP Sleep & Health (2012-2015): link

Publications: Pubmed

Synergies with other sleep research groups:  Malcolm Kohler, Konrad Bloch

Prof. Erich Seifritz, MD

member

 

Psychiatric Hospital, University of Zurich

erich.seifritz@bli.uzh.ch

Research fields: Clinical sleep research

KFSP Sleep & Health (2012-2018): link

Publications: Pubmed

Benjamin Stucky, PhD

member

 

Institute of Pharmacology and Toxicology, UZH

Postdoctoral fellow (Group Landolt)

benjamin.stucky@pharma.uzh.ch

Website: Human sleep Psychopharmacology Laboratory

Research fields: Basic human sleep research, new technologies

Research Focus: Pharmacogenetic approaches to determine the contribution of genetic variants to slep phenotypes. Effects of caffeine on sleep and health. Applying and developping novel statistical learning tools. Consciousness research.

Methodological expertise: analyse of high-dimensional datasets, LASSO, R,

Publications: Pubmed

Laura Tüshaus, PhD

member

 

ETH Zurich

Department of Health Sciences and Technology

Mobile Health Systems Lab (Group Karlen)

Postdoctoral fellow 

laura.tueshaus@hest.ethz.ch

Website: Link

Research fields: New technologies

Publications: Pubmed

HMZ Flagship SleepLoop: link

Philipp Valko, MD

member

 

Department of Neurology, University Hospital Zurich

Senior scientist (Group Baumann)

philipp.valko@usz.ch

Research fields: Clinical sleep research

Publications: Pubmed

University Children's Hospital Zurich

Amandine Valomon, PhD

member

 

University of Wisconsin-Madison

Postdoctoral fellow (Prof. G. Tononi)

valomon@wisc.edu

Research fields: Basic sleep research

Publications: Pubmed

 

Helen Werner, PhD

werner

 

University Children's Hospital Zurich

Postdoctoral fellow (Group Jenni)

helene.werner@kispi.uzh.ch

Research fields: Basic preclinical and human sleep research

Research Focus: Sleep behavior and sleep problems in infants and young children Sleep phase preference among adolescents. Associations between school start times in the morning and adolescents' sleep deficits. 

Questions driving my research: How can we improve the framework conditions for lower sleep deficits among adolescents? How can we improve behavioral sleep problems in infants and young children?

Methodological expertise: Questionnaires, Actigraphy

Publications: Pubmed

Synergies with other sleep research groups: Salome Kurth

Esther Werth, PhD

member

 

Department of Neurology, University Hospital Zurich

Senior scientist (Group Baumann)

Head of the sleep laboratory (Neurology)

esther.werth@usz.ch

Research fields: Basic human sleep research, chronobiology, clinical sleep research, new technologies

Research Focus: The overall goals of my research are to characterize sleep-wake function in brain disorders and to elucidate brain mechanism involved in sleep-wake regulation.

Questions driving my research: How strong is the role of the circadian system in central hypersomnolence disorders?

Methodological expertise: quantitative sleep EEG, clinical expertise

Publications: Pubmed

Synergies with other sleep research groups: Roger Gassert (ETH Zurich)

 

SHZ Junior Members:

Franziska Ryser, PhD candidate (fryser@student.ethz.ch)

Elisabeth Wilhelm, PhD

member

 

ETH Zurich

Sensory-Motor Systems Lab

Postdoctoral fellow (Group Riener)

elisabeth.wilhelm@hest.ethz.ch

Research fields: New technologies

Methodological expertise: Robotics

Synergies with other sleep research groups:  Malcolm Kohler, Peter Achermann, Hans-Peter Landolt, Oskar Jenni.

Publications: Pubmed