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SHZ full and associate members:
Maren Cordi, PhD (associate)
Prof. Walter Karlen, PhD (associate)
à Daniela Latshang, MD
Caroline Lustenberger, PhD (associate)
Sarah Schoch, PhD (associate)
Laura Tüshaus, PhD (associate)
Elisabeth Wilhelm, PhD (associate)
à Stefan Lakämper, PhD
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Department of Neurology, University Hospital Zurich Research fields: Basic & clinical sleep research, new technologies Research Focus: Neurology, Neurodegenerative diseases, Parkinson, Sleep disorders KFSP Sleep & Health (2012-2018): link HMZ Flagship SleepLoop: link Collaborative projects with: Reto Huber, Walter Karlen, Erich Seifritz, Hans-Peter Landolt Publications: Pubmed
SHZ Junior Members: Sedef Kollarik, PhD candidate (sedef.erdogan@usz.ch) Carlos Gonçalves Moreira, PhD candidate (carlos.goncalvesmoreira@usz.ch) |
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Department of Pulmonology, University Hospital Zurich Website: Department of Pulmonology Research fields: Clinical sleep research, new technologies Research Focus: Sleep related breathing disorders (clinical manifestation, diagnosis and treatmen), interactions between hypoxia and sleep Questions driving my research: What are the physiological mechanisms of sleep related breathing disorders? How can they be diagnosed? How can they be treated? Methodological expertise: Broad physiological and clinical monitoring of control of breathing, ventilation and sleep Randomized clinical trials in the hospital and field setting Publications: Pubmed Synergies with other sleep research groups: Silvia Ulrich, Malcolm Kohler, Reto Huber |
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University of Fribourg, Department of Psychology Postdoctoral fellow Team Cognitive Biopsychology and Methods (Prof. Björn Rasch) Publications:Pubmed |
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University Children's Hospital Zurich Website: Link Research fields: Basic human sleep research, new technologies Research Focus: Sleep and brain maturation, Learning related plasticity and sleep regulation, Neurodevelopmental disorders, Neuromodulation during sleep, Local sleep, Multimodal imaging during sleep Questions driving my research: What is sleep recovery? Does sleep play an active part in brain maturation? What is the potential of neuromodulation techniques during sleep as a therapeutic intervention? What is the relationship between different imaging modalities and sleep oscillations? Methodological expertise: High-density EEG, Closed-loop acoustic stimulation, Multimodal neurimaging (MRI, MR spectroscopy, EEG) KFSP Sleep & Health (2012-2018): link HMZ Flagship SleepLoop: link Publications: Pubmed Synergies with other sleep research groups: Hans-Peter Landolt, Steven Brown, Christian Baumann Walter Karlen, Daniel Brandeis (UZH), Oskar Jenni, Bernhard Schmitt (University Children's Hospital Zurich)
SHZ Junior Members: Jelena Skorucak, PhD (jelena.skorucak@pharma.uzh.ch) Vanessa Kasties, PhD candidate ( vanessa.kasties@kispi.uzh.ch) Maria Eleni Dimitriades, PhD candidate (maryeleni.dimitriades@kispi.uzh.ch) |
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University Children's Hospital Zurich Publications: Pubmed |
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University of Ulm Institute of Biomedical Engineering Website: Link Research fields: New technologies Research Focus: Biomedical signal processing, mobile health (mHealth), adaptive algorithms and systems, embedded and wearable devices, mobile computing, biomedical sensors and systems, global health, appropriate devices, decision support, artificial intelligence, machine learning, pulse oximeter, capnography, pneumonia, sleep. HMZ Flagship SleepLoop: link Publications: Pubmed Synergies with other sleep research groups: Christian Baumann, Reto Huber Twitter: @karliwalti |
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Department of Psychiatry Psychotherapy and Psychosomatics (website) KFSP Sleep & Health (2012-2018): link Publications: Pubmed |
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Department of Pulmonology, University Hospital Zurich Director Website: Department of Pulmonology Research fields: Clinical sleep research, new technologies KFSP Sleep & Health (2012-2018): link HMZ Flagship Exhalomics: Link Publications: Pubmed
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Institute of Pharmacology and Toxicology, UZH konstantinos.kompotis@pharma.uzh.ch Websites: The Brown Lab Research fields: Basic sleep research, chronobiology Research Focus: My research so far has been focused on sleep homeostasis and circadian rhythms in rodent models. 1 am mainly interested in the regulation of sleep spanning from the molecular level (sleep-associated non-coding RNAs ), to the network level ( opto/chemogenetic interrogation of circadian populations impinging on the sleep circuitry), to the interactions with peripheral sensory systems (vestibular stimulation). 1 am currently working on the network level and the circadian-sleep interactions. Questions driving my research: In terms of a broader context, 1 am curious as to what exactly sleep means for the individual neuron, the local population, as weil as the expanded network, and which aspects of sleep can be manipulated at these levels. For instance, can a single microRNA of a neuronal population affect the power of a given band during a given state? Can neuronal populations responsible for other processes (e.g circadian or energy homeostasis) have an impact directly on the sleep circuitry, and if so, where is this "sum-force calculation" happening in the brain? What aspects of sensory stimulation are important to improve sleep, and can we manipulate deeper structures in their pathway with different means? Methodological expertise: rodent electrophysiology, opto/chemogenetic manipulation of neuronal circuitry, brain clearance, sleep behavior analysis Publications: Pubmed Synergies with other sleep research groups: Steven Brown |
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Institute of Forensic Medicine, University of Zurich Websites: Forensic Pharmacology & Toxicology Research fields: Basic sleep research, new technologies, applied research Research Focus: Originally started as analytical toxicologists in the field of applied research in forensic toxicology, our group broadened its research field. Besides excellent skills in different kind of hyphenated mass spectrometry techniques, more and more additional fields were conquered: metabolism studies, postmortem research, metabolomics, application of machine learning for high-resolution MS/MS data. Regarding sleep and health, we are interested in the changes in the metabolome of sleep deprived people and in finding a reliable biomarker for fatigue. Questions driving my research: What are the changes in the human body under sleep deprivation? Can we establish a (maybe even quantitative) biomarker for fatigue? Methodological expertise: Analytical determination of almost every endogenous and exogenous compound in biological matrices (blood, urine, hair, tissues, oral fluid, liquor etc.). Publications: orcid Synergies with other sleep research groups: Hans Peter Landolt, Dario Dornbierer |
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Department of Pulmonology, University Hospital Zurich Department of Psychology, University of Fribourg Websites: Baby Sleep Lab; Team Development of Sleep Regulation Research fields: Basic human sleep research Research Focus: Development of sleep regulation in childhood Questions driving my research: Which parameters of infant sleep behavior represent a health risk for neurodevelopment? Are early sleep patterns a trait and thus persist throughout later life? Are there associations between sleep and the gut bacteria? Methodological expertise: High-density EEG during sleep KFSP Sleep & Health (2016-2018): link Publications: Pubmed Synergies with other sleep research groups: Malcolm Kohler, Reto Huber, Oskar Jenni, Steven Brown, Walter Karlen |
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Institute of Pharmacology and Toxicology, UZH Website: Human sleep Psychopharmacology Laboratory Research fields: Basic human sleep research, clinical sleep research Research Focus: Physiological processes and neurochemical mechanisms regulating wakefulness and sleep in health and disease. Questions driving my research: What are the molecular mechanisms underlying the transition from wakefulness to sleep and from sleep to wakefulness? Who is vulnerable to sleep deprivation? How does sleep promote health? Can sleep be enhanced to benefit health? Methodological expertise: Multidisciplinary, integrative approach combining pharmacogenetics, neurophysiology (polysomnography and [high-density] EEG), molecular brain imaging (PET, MRS) and neurocognitive testing KFSP Sleep & Health (2012-2018): link Publications: Pubmed Synergies with other sleep research groups (Zurich): Christian Baumann, Erich Seifritz, Simon M. Ametamey (ETH Zürich), Reto Huber
SHZ Junior Members: Ian Clark, PhD candidate (ian.clark@uzh.ch) Wolfgang Ganglberger, PhD candidate (WGANGLBERGER@mgh.harvard.edu)
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ETH Zurich Department of Health Sciences and Technology Neural Control of Movement Lab (Pof. N. Wenderoth) Research fields: Basic human sleep research, new technologies Research Focus: link Methodological expertise: HMZ Flagship SleepLoop: link Publications: Pubmed Synergies with other sleep research groups: Christian Baumann, Reto Huber, Walter Karlen, Nicole Wenderoth |
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Department of Neurology, University Hospital Zurich Senior Scientist (Group Baumann) Research fields: Basic human sleep research, clinical sleep research, new technologies Research Focus: Psycho-physiological sleep research in health and disease, with a special emphasis on the effects chronic sleep restriction. Questions driving my research: How do sleep physiological processes influence brain functioning and corresponding behavior during subsequent wakefulness? What are the consequences of chronically insufficient sleep and the underlying mechanisms thereof? How do sleep physiological processes contribute to symptoms and progression of a neurological disease like Parkinson? Methodological expertise: Performance of highly controlled, experimental sleep studies (e.g. sleep restriction protocols), including state-of-the-art neuroscientific methods like high-density sleep electroencephalography (hd-EEG) and comprehensive behavioral testing like elaborate decision-making paradigms. Publications: Pubmed Synergies with other sleep research groups: Reto Huber, Walter Karlen, Ernst Fehr (Department of Economics, UZH), Helga Fehr-Duda, (Institute of Banking and Finance, UZH), Ruth O’Gorman Tuura (Center for MR-Research, University Children's Hospital Zurich), Caroline Lustenberger, Salome Kurth |
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University Children's Hospital Zurich alexander.moeller@kispi.uzh.ch Research fields: Clinical sleep research Research Focus: Sleep disordered breathing in children and effects on development Methodological expertise: clinical expertise Synergies with other sleep research groups: Reto Huber, Oskar Jenni, Malcolm Kohler |
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Department of Neurology, University Hospital Zurich Senior scientist (Group Baumann) Research fields: Basic preclinical sleep research Research Focus: The focus of our research is exploring the role of slow-wave sleep in the levels of brain proteins that lead to neurodegeneration. Aiming at implementing translational and highly specific slow-wave sleep modulation strategies in transgenic rodent models of disease, we develop innovative techniques, such as closed-loop acoustic stimulation of slow oscillations. Our ultimate goal is providing tools for and proof that modulations of slow-wave sleep regulate protein clearance in the sleeping brain and, therefore, could be translated into novel non-invasive human therapies against Alzheimer and Parkinson Disease. Questions driving my research: What restorative and/or neuroprotective processes unfold in the sleeping brain? s slow-wave sleep a key player to their regulation and execution? And, therefore: Could slow-wave sleep modulation be used to influence the course of neuropathological processes? Methodological expertise: In vivo electrophysiology, Pharmacological modulation of slow waves, Acoustic modulation of slow waves, Behavioral testing, Histopathology Publications: Pubmed Synergies with other sleep research groups: Reto Huber |
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University Children's Hospital Zurich Research fields: Basic and clinical sleep research, new technologies Research Focus: As a physicist with a background in medical imaging (particularly MRI), my primary scientific interests are focused on advanced methods for evaluating brain physiology, including arterial spin labelling perfusion MRI, MR spectroscopy, diffusion tensor MRI, functional MRI, and quantitative MR Relaxometry. In addition to performing methodological studies with an aim to improve or cross-validate these methods, I have also performed a number of multimodal studies utilising multiple, complementary imaging methods to give a more complete and detailed picture of tissue morphology and function. This approach has yielded novel insight into the brain changes associated with sleep, as well as insight into brain development in children, both in healthy populations and in those at risk for neurodevelopmental impairment. Questions driving my research: My research is inspired by a number of questions. On the methodological side, I am interested to push forward the imaging methods (and image analysis methods) available both to the clinics and to researchers interested in measuring brain physiology with MRI. In addition, I am interested in the development of brain structure and function in neonates, children, and adolescents, and in the assessment of neuroimaging biomarkers for outcome in children at risk for developmental impairment. Recently, I have also become fascinated with the potential role of sleep in clearing the brain, and how we might be able to measure and characterise this process in vivo with MRI. Methodological expertise: MRI methods: arterial spin labelling perfusion MRI, MR spectroscopy, diffusion tensor MRI, functional MRI, quantitative MR Relaxometry, simultaneous EEG-fMRI Publications: Pubmed Synergies with other sleep research groups: Christian Baumann, Reto Huber, Walter Karlen, Hans-Peter Landolt SHZ Junior Members Lena Meinhold, PhD candidate (lena.meinhold@kispi.uzh.ch) |
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Consultant in Neurology, Psychiatry & Psychotherapy Research fields: Clinical sleep research, new technologies Research Focus: Neuropsychiatry with a sex- and gender-specific focus, Neurodegenerative diseases, Neurotrauma outcome, Sleep disorders after brain injuries over the lifespan Questions driving my research: What are the patterns and frequencies of sleep disorders in patients suffering from brain injuries? Is there a sex- and gender-specific difference in sleep disorders after brain injuries? How can they be diagnosed? How can they be treated? How can a better sleep decrease the neuropsychiatric long-term burden after brain injuries? Methodological expertise: Clinical, fluid, and advanced imaging markers after brain injuries, neuropsychiatric sleep assessment, psychometric and instrumental assessments including polygraphy, polysomnography and actigraphy Publications: Pubmed Twitter: @KatrinRauen Synergies with other sleep research groups: Christian Baumann, Reto Huber, Sarah Schiebler, Erich Seifritz, Roland von Känel, Esther Werth |
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Faculty of Medicine (UZH), ETH Zurich Research fields: Basic human sleep research, new technologies Research Focus: Development of an autonomous robotic platform to improve sleep quality using vestibular stimulation. Controlled positional therapy to reduce snoring. Questions driving my research: Improvement of health and well-being related to sleep. Methodological expertise: Man-machine interaction. Rehabilitation Engineering Biomechatronics & Biomedical Engineering. Virtual reality. Transfer of Technologies into Neurorehabilitation Publications: Pubmed Synergies with other sleep research groups: Hans-Peter Landolt, Reto Huber, Malcolm Kohler
SHZ Junior member: Rachel van Sluijs, PhD candidate (rachel.vansluijs@hest.ethz.ch)
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Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich Website: Klinik für Konsiliarpsychiatrie und Psychosomatik Research fields: Clinical sleep research Research Focus: Effects of different treatments (CBT-I, hypnotherapy, hypnotic drugs) of sleep disorders and sleep disturbances in mental and psychosomatic disorders Questions driving my research: Which methods can effectively improve the diagnostic procedures and the treatment of sleep disturbances in psychiatric and psychosomatic disorders? Methodological expertise: Completed training as a specialist and diploma in psychiatry and psychotherapy; Training in psychosomatic medicine and Consultation-Liaison-Psychiatry; Diploma of Cognitive Behavioral Therapy; Diploma of Advanced Studies in Psychotraumatology; Master in Hypnotherapy Synergies with other sleep research groups: Philipp Valko, Roland von Känel |
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Donders Institute for Brain, Cognition and Behaviour (The Netherland) Postdoctoral fellow Website: Donders Sleep & Memory Lab Research fields: Basic human sleep research Research Focus: Dreams, sleep and development Questions driving my research: What roles do dreams play in memory consolidation during the night? What role do sleep and dreams play in development? Methodological expertise: EEG, Actigraphy, Microbiome, Dream report collection Publications: Pubmed Synergies with other sleep research groups: Salome Kurth |
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Department of Neurology, University Hospital Zurich Postdoctoral fellow (Group Baumann) Website: Dr. med. Simon Jakob Schreiner USZ Research fields: Clinical sleep research, new technologies Research Focus: Role and therapeutic potential of sleep in neurodegenerative disease, Alzheimer and Parkinson in particular. Methodological expertise: Quantitative sleep EEG, neuroimaging, wearable devices, sleep modulation (e.g. auditory stimulation) Publications: Pubmed Twitter: @SJ_Schreiner Synergies with other sleep research groups: Walter Karlen, Reto Huber, Angelina Maric |
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Department of Pulmonology, University Hospital Zurich Senior scientist (Group Kohler) Website: Department of Pulmonology Research fields: Clinical sleep research Research Focus: Pathophysiological consequences of obstructive sleep apnoea and chronic pulmonary disease, cardiovascular and metabolic effects of continuous positive airway pressure therapy and emerging treatment approaches for sleep- disordered breathing. Long-term outcome of chronic respiatory failure trated by non invasive ventilation, haemodynamic effect of positive pressure ventilation. Neural respiratory drive/electromyography in different respiratory diseases. KFSP Sleep & Health (2012-2015): link Publications: Pubmed Synergies with other sleep research groups: Malcolm Kohler, Konrad Bloch |
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University Psychiatric Hospital Director Research fields: Clinical sleep research KFSP Sleep & Health (2012-2018): link Publications: Pubmed |
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Children's Hospital Zurich, University of Zurich Postdoctoral fellow (Group Huber) Research fields: Basic human sleep research, clinical sleep research, new technologies Research Focus: Artificial intelligence methods for pattern detection in sleep and wake EEG. Large-scale data analysis of epilepsy patients. Methodological expertise: Artificial intelligence, biomedical signal processing Synergies with other sleep research groups: Peter Achermann, Walter Karlen Publications: Pubmed |
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ETH Zurich Department of Health Sciences and Technology Mobile Health Systems Lab (Group Karlen) Postdoctoral fellow Website: Link Research fields: New technologies Publications: Pubmed HMZ Flagship SleepLoop: link |
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Department of Neurology, University Hospital Zurich Senior scientist (Group Baumann) Research fields: Clinical sleep research Publications: Pubmed University Children's Hospital Zurich |
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Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine University Hospital Zurich Director Website: Klinik für Konsiliarpsychiatrie und Psychosomatik Research fields: clinical sleep research Research Focus: sleep health, sleep and risk of cardiovascular disease, chronic stress and sleep, sleep in psychiatric and psychosomatic disorders Questions driving my research: What are the psychological, autonomic, neuroendocrine, immunological and cardiometabolic mechanisms and interactions underlying the health risk of poor sleep? Methodological expertise: Stress physiology, biomarkers (inflammation and hemostasis), psychometric assessment, clinical expertise in sleep medicine Synergies with other sleep research groups: Sarah Schiebler Publications: Pubmed |
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University Children's Hospital Zurich Postdoctoral fellow (Group Jenni) Research fields: Basic preclinical and human sleep research Research Focus: Sleep behavior and sleep problems in infants and young children Sleep phase preference among adolescents. Associations between school start times in the morning and adolescents' sleep deficits. Questions driving my research: How can we improve the framework conditions for lower sleep deficits among adolescents? How can we improve behavioral sleep problems in infants and young children? Methodological expertise: Questionnaires, Actigraphy Publications: Pubmed Synergies with other sleep research groups: Salome Kurth |
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Department of Neurology, University Hospital Zurich Senior scientist (Group Baumann) Head of the sleep laboratory (Neurology) Research fields: Basic human sleep research, chronobiology, clinical sleep research, new technologies Research Focus: The overall goals of my research are to characterize sleep-wake function in brain disorders and to elucidate brain mechanism involved in sleep-wake regulation. Questions driving my research: How strong is the role of the circadian system in central hypersomnolence disorders? Methodological expertise: quantitative sleep EEG, clinical expertise Publications: Pubmed Synergies with other sleep research groups: Roger Gassert (ETH Zurich) |
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ETH Zurich Sensory-Motor Systems Lab Postdoctoral fellow (Group Riener) elisabeth.wilhelm@hest.ethz.ch Research fields: New technologies Methodological expertise: Robotics Synergies with other sleep research groups: Malcolm Kohler, Peter Achermann, Hans-Peter Landolt, Oskar Jenni. Publications: Pubmed |
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University Children's Hospital Zurich, UZH Research fields: Basic sleep research - Human, Chlinical sleep research, New technologies, applied research Research focus: Basic human sleep research, brain stimulation techniques, epilepsy, Neuromodulation during sleep, Local sleep, Deep brain recordings in humans Questions driving my research: What are the different synchronization processes to generate NREM sleep specific oscillations? And how can these synchronization processes be manipulated? What functions do these different oscillations serve? What is the relationship between epileptiform discharges and the physiological brain oscillations during NREM sleep? Methodological expertise: High-density EEG, Closed-loop acoustic stimulation, Deep Brain stimulation Synergies with other sleep research groups: Reto Huber, Lukas Imbach, Christian Baumann, Angelina Maric Publications: Orcid
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